Changes of the Infusion Rate in Insulin Pump Treatment

• Status: Completed
• Trial end date: 2008-10-01
• Target enrollment: 0
• Participant gender: All

Summary

A pharmacokinetic study of insulin pump treatment using Insulin Aspart. The study consist of three different periods A, B and C where a constant the insulin infusion rate is given during the periods. In period B and C will the infusion start with a bolus.

It will be investigated if a steady state of insulin will be obtained faster in period B and C then A.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Aarhus University Hospital
• Collaborator: Novo Nordisk A/S
• Treatments: Insulin; Insulin Aspart; Insulin degludec, insulin aspart drug combination; Insulin, Globin Zinc; Insulin, Long-Acting

Criteria

Inclusion Criteria:

• Informed consent

• Healthy volunteer

• Men and women between ≥18 and <50 years

• Women in the child-bearing age should be sufficient protected against pregnancy (use birth control pill or intrauterine device or be sterilized or hysterectomized)

• BMI between 18-30 kg/m^2 (both included)

Exclusion Criteria:

• Suspected or known allergy against the drug used in the study or similar drugs

• Previous history of endocrinology disease (including Diabetes Mellitus)

• Suspected or known alcohol- or drug abuse

• Any disease influencing the study, evaluated by the investigator

• Pregnancy, breast-feeding or the wish of becoming pregnant during the study period. Furthermore women in the child bearing age not sufficient protected against pregnancy (sufficient is: use of birth control pill or intrauterine device or be sterilized or hysterectomized)

• Participation in other research projects during the last 3 months before this project