Changes to the Retina Following Anti-VEGF Treatments for Diabetic Macular Edema

• Status: Completed
• Trial end date: 2017-08-01
• Target enrollment: 0
• Participant gender: All

Summary

anti-VEGF therapy is an established method to control leakage and abnormal growth of retinal blood vessels. Questions on the long-term effect on the retina, intraocular pressure and on the overall retinal perfusion from these treatments remain to be answered. The purpose of the study was to evaluate changes in the retina following anti-VEGF treatment over time, using structural and functional diagnostic tests.

• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Lawson Health Research Institute
• Treatments: Bevacizumab; Ranibizumab

Criteria

Inclusion Criteria:

• DME patients

• Require anti-VEGF injections in at least one eye

Exclusion Criteria:

• Advanced lens opacity or cataract that could affect diagnostic testing

• Prior retinal treatment (PRP, focal laser or surgery within 6 months of participation)