Characterization of Sympathetic Nerve Activity in Stress Cardiomyopathy

• Status: Terminated
• Trial end date: 2012-07-01
• Target enrollment: 0
• Participant gender: All

Summary

Stress (Takotsubo) cardiomyopathy (SC) is a peculiar form of acute, reversible myocardial dysfunction predominantly affecting the apical and mid left ventricular segments.

In this institution over the last two to three years the investigators have identified more than a dozen patients with stress cardiomyopathy. The investigators' overarching goal is to characterize these individuals with the hope of identifying risk factors and developing strategies to prevent the occurrence of SC in situations where the likelihood in susceptible individuals may be high.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University of Missouri-Columbia
• Treatments: Nitroprusside; Oxymetazoline; Phenylephrine

Criteria

Inclusion Criteria:

• Diagnosis of stress cardiomyopathy in the past

Exclusion Criteria:

• Coronary artery disease (CAD), primary coronary intervention (PCI) or coronary artery bypass graft (CABG)

• Cardiac dysfunction

• Heart failure

• Significant arrhythmias

• Severe chronic obstructive pulmonary disease (COPD)

• Diabetic neuropathy

• Pregnancy