Overview
Characterization of the Prosocial and Prosexual Effects of GHB
Status:
Completed
Completed
Trial end date:
2014-12-01
2014-12-01
Target enrollment:
0
0
Participant gender:
Male
Male
Summary
The purpose of this study is to determine whether gamma-Hydroxybutyrate (GHB) has prosocial and prosexual effects in healthy male participants, and to characterize these putative effects via behavioral tests, functional magnetic resonance imaging (fMRI), electroencephalography (EEG), and neuroendocrine parameters. The investigators predict that GHB in fact has prosocial and prosexual effects which can be neurobiologically characterized using the assessed methods. Such effects would be of high interest for the treatment of mental disorders which involve impairments of social interaction and sexual function such as major depression or autism.Phase:
N/AAccepts Healthy Volunteers?
Accepts Healthy VolunteersDetails
Lead Sponsor:
University of ZurichCollaborators:
University of Freiburg
University of Regensburg
University of Salerno
University of ViennaTreatments:
Sodium Oxybate
Criteria
Inclusion Criteria:- Healthy male subjects.
Exclusion Criteria:
- Any Axis-I DSM-IV psychiatric disorder, any form of addiction or regular illegal drug
use (lifetime use >5 occasions) with exception of occasional cannabis use, a lifetime
history of GHB use, a neurological disorder or head injury, clinically relevant
medical diseases, a family history of schizophrenia or bipolar disorder, and any use
of prescription drugs.