Overview

Chemotherapy Before and After Surgery in Treating Children With Wilm's Tumor

Status:
Unknown status
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Giving combination chemotherapy before surgery may shrink the tumor so it can be removed during surgery. Giving more chemotherapy after surgery may kill any remaining tumor cells. It is not yet known which chemotherapy regimen after surgery is most effective in treating Wilm's tumor. PURPOSE: Phase III trial to study the effectiveness of chemotherapy before and after surgery in treating children who have Wilm's tumor.
Phase:
Phase 3
Details
Lead Sponsor:
University of Leicester
Collaborators:
Children's Cancer and Leukaemia Group
Gesellschaft fur Padiatrische Onkologie und Hamatologie - Germany
Societe Francaise Oncologie Pediatrique
Treatments:
Carboplatin
Cyclophosphamide
Dactinomycin
Doxorubicin
Etoposide
Liposomal doxorubicin
Vincristine