Chemotherapy Followed By Vaccine Therapy in Treating Patients With Extensive-Stage Small Cell Lung Cancer
Status:
Completed
Trial end date:
2014-05-01
Target enrollment:
Participant gender:
Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so
they stop growing or die. Vaccines made from a gene-modified virus may make the body build an
immune response to kill tumor cells. Combining vaccine therapy with chemotherapy may kill
more tumor cells.
PURPOSE: Phase I/II trial to study the effectiveness of chemotherapy followed by adenovirus
p53 vaccine therapy in treating patients who have extensive-stage small cell lung cancer.
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
H. Lee Moffitt Cancer Center and Research Institute