Chemotherapy Followed by Biological Therapy in Treating Patients With Stage IV Melanoma That Cannot be Treated With Surgery
Status:
Completed
Trial end date:
2003-12-01
Target enrollment:
Participant gender:
Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so
they stop growing or die. Biological therapies such as interleukin-2 and interferon alfa
stimulate a person's white blood cells to kill cancer cells or may interfere with the growth
of cancer cells. Combining chemotherapy with biological therapies may kill more tumor cells.
PURPOSE: Phase II trial to study the effectiveness of temozolomide followed by sargramostim,
interleukin-2, and interferon alfa in treating patients who have stage IV melanoma that
cannot be treated with surgery.