Overview

Chemotherapy With or Without Trastuzumab in Treating Patients With Metastatic Osteosarcoma

Status:
Completed
Trial end date:
2007-05-01
Target enrollment:
Participant gender:
Summary
Drugs used in chemotherapy work in different ways to stop tumor cells from dividing so they stop growing or die. Monoclonal antibodies such as trastuzumab can locate tumor cells and kill them without harming normal cells. Combining monoclonal antibody therapy with chemotherapy may kill more tumor cells. Phase II trial to study the effectiveness of chemotherapy with or without trastuzumab in treating patients who have metastatic osteosarcoma
Phase:
Phase 2
Details
Lead Sponsor:
National Cancer Institute (NCI)
Treatments:
Doxorubicin
Etoposide
Etoposide phosphate
Ifosfamide
Leucovorin
Levoleucovorin
Liposomal doxorubicin
Methotrexate
Trastuzumab