Chemotherapy and Proton Radiation for the Treatment of Locally Advanced Lung Cancer

• Status: Terminated
• Trial end date: 2011-06-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to determine the effectiveness of proton beam radiotherapy combined with chemotherapy for treatment of locally advanced non-small cell lung cancer.

• Phase: Phase 1/Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Loma Linda University
• Treatments: Carboplatin; Paclitaxel

Criteria

Inclusion Criteria:

• Clinical stage 2, 3A or 3B (unresectable)

• Histologic evidence of non-small cell carcinoma

• Age > 18 years

• Karnofsky performance status 70 or greater

• No prior radiation to the chest

• No previous chemotherapy

Exclusion Criteria:

• Clinical stage 1 or 4

• Previous malignancies except for non-melanoma skin cancer unless disease free for > 3 years