Chemotherapy and Rituximab With Peripheral Stem Cell Transplantation in Treating Patients With Mantle Cell Lymphoma
Status:
Completed
Trial end date:
2009-09-01
Target enrollment:
Participant gender:
Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so
they stop growing or die. Monoclonal antibodies such as rituximab can locate tumor cells and
either kill them or deliver tumor-killing substances to them without harming normal cells.
Peripheral stem cell transplantation may allow the doctor to give higher doses of
chemotherapy drugs and kill more cancer cells.
PURPOSE: Phase II trial to study the effectiveness of combining chemotherapy and rituximab
with peripheral stem cell transplantation in treating patients who have mantle cell lymphoma.