Chemotherapy or Observation in Treating Patients With Early Stage Non-Small Cell Lung Cancer
Status:
Terminated
Trial end date:
2012-11-01
Target enrollment:
Participant gender:
Summary
RATIONALE: Drugs used in chemotherapy, such as vinorelbine, cisplatin, docetaxel,
gemcitabine, and pemetrexed disodium, work in different ways to stop the growth of tumor
cells, either by killing the cells or by stopping them from dividing. Sometimes after
surgery, the tumor may not need more treatment until it progresses. In this case, observation
may be sufficient. It is not yet known whether chemotherapy is more effective than
observation in treating patients who have undergone surgery for stage I non-small cell lung
cancer.
PURPOSE: This randomized phase III trial is studying four chemotherapy regimens to see how
well they work compared with observation in treating patients with early stage non-small cell
lung cancer.