Children With HIV and Asthma (CHIVAS)

• Status: Completed
• Trial end date: 2015-12-01
• Target enrollment: 0
• Participant gender: All

Summary

To explore allergen-specific effector and regulatory T cell response in HIV-infected children before and after HAART initiation

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: The HIV Netherlands Australia Thailand Research Collaboration
• Collaborators: Chulalongkorn University; National Health Security Office, Thailand

Criteria

Inclusion Criteria:

1. Children aged 2-18 years

2. Parent signed inform consent and children signed assent form

3. Children who are starting highly active antiretroviral therapy (HAART) due to clinical indication or switching HAART due to treatment failure within 45 days after screening visit

Exclusion Criteria:

1. Pregnancy

2. History of chronic lung disease including lymphoid interstitial pneumonitis (LIP), and bronchopulmonary dysplasia (BPD).

3. Active opportunistic infections i.e. pulmonary tuberculosis, PCP, pneumonia

4. Conditions limiting ability of subject to comprehend questionnaires (i.e. mental retardation).