Chlorhydrate of Ropivacaine and Breast Cancer Surgery

• Status: Completed
• Trial end date: 2008-11-01
• Target enrollment: 0
• Participant gender: Female

Summary

The aim of the study is to evaluate the effect of local anesthetic (chlorhydrate of ropivacaine) to prevent chronic pain after breast surgery for cancer.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Institut Curie
• Collaborators: AstraZeneca; Gustave Roussy, Cancer Campus, Grand Paris
• Treatments: Ropivacaine

Criteria

Inclusion Criteria:

• Breast cancer patients treated by conservative surgery with axillary node dissection or treated by mastectomy with or without axillary node dissection or sentinel lymph node biopsy.

• ASA physical status 1, 2 or 3

• With a minimum life expectancy of 2 years

• Written informed consent

Exclusion Criteria:

• Any previous cancer other than breast cancer

• Allergies to local anesthesic and morphine

• Reported history of drug

• Pregnancy

• Homolateral breast surgery during the last 3 years

• Analgesic use pre-operatively

• Renal, pulmonary or liver major dysfunction

• Active malignant disease

• Unable to follow the protocol for any reason