Cholecalciferol Supplementation on Disease Activity, Fatigue and Bone Mass on Juvenile Systemic Lupus Erythematosus.
Status:
Completed
Trial end date:
2014-02-01
Target enrollment:
Participant gender:
Summary
The potential role of vitamin D on disease susceptibility, activity and severity has been
considered for several autoimmune rheumatologic diseases include systemic lupus erythematosus
(SLE) . Although, there are few studies of vitamin D supplementation in SLE patients,
especially in Juvenile Onset Systemic Lupus Erythematosus (JoSLE).
The objective of this study is to evaluate the effect of vitamin D supplementation
(cholecalciferol 50.000 international units (IU)/week for 24 weeks) on disease activity
(clinical and laboratory parameters), fatigue and bone mass.