Cholesterol Metabolites as Markers for CYP3A Induction
Status:
Completed
Trial end date:
2011-07-01
Target enrollment:
Participant gender:
Summary
The objectives of this study are:
- To investigate if the endogenous cholesterol metabolite, 4beta-OHcholesterol could be
used as a marker for induction of cytochrome P450 (CYP) 3A4.
- To compare 4beta-OHcholesterol with midazolam as a marker for induction of CYP3A4.