Choroidal Thickness and Its Correlations With Ocular Parameters in Primary Open-angle Glaucoma

• Status: Completed
• Trial end date: 2015-04-01
• Target enrollment: 0
• Participant gender: All

Summary

Glaucoma is one of the leading causes of blindness worldwide that is a chronic public health problem. Unfortunately, glaucoma can be diagnosed when the disease reaches a certain level in today's conditions. The aim of this study was to investigate the diagnostic methods that can diagnose glaucoma before it reaches the advanced level and to identify pathophysiological processes. In this study, choroidal thickness was investigated in primary open-angle glaucoma cases and its correlations with OCT and multifocal ERG parameters were evaluated.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Afyon Kocatepe University Hospital
• Treatments: Bimatoprost; Brimonidine Tartrate; Brinzolamide; Cloprostenol; Dorzolamide; Latanoprost; Ophthalmic Solutions; Timolol; Travoprost

Criteria

Inclusion Criteria for the glaucoma group:

• the best corrected visual acuity (BCVA) of 0.6 and above

• Intraocular pressure being above 21 mmHg

• Detection of open-angle by gonioscopy

• Detection of glaucomatous optic disc pitting by fundus examination

• Visual field defect in perimetry (Carl Zeiss Meditec AG, Germany)

Exclusion Criteria for the glaucoma group:

• A secondary cause of glaucoma

• Angle-closure in gonioscopic examination

• Corneal opacity or cataract at the level that may affect imaging, vitreous pathology

• Intravitreal hemorrhage that may affect fundus appearance, retinal pathology

• Chorioretinopathy, optic neuropathy, optic disc pathology, spherical refractive error of 6D and above, cylindrical refraction error of 3D and above and systemic diseases which may affect ocular blood flow

Inclusion Criteria for the healthy group:

• The best corrected visual acuity (BCVA) of 0.8 and above

Exclusion Criteria for the healthy group:

• Presence of systemic disease that may affect choroid blood flow

• Ocular conditions that may affect test measurements