Chronic Prostatitis Collaborative Research Network Clinical Trial- Ciprofloxacin and Tamsulosin
Status:
Completed
Trial end date:
2003-08-31
Target enrollment:
Participant gender:
Summary
Although the cause of chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is unknown,
physicians sometimes try to treat it with antibiotics or alpha-receptor blockers.
In this multicenter, double-blind factorial trial, 196 men with moderately severe CP/CPPS
were randomly assigned to 6 weeks of treatment with ciprofloxacin, tamsulosin, both drugs, or
placebo. Neither ciprofloxacin nor tamsulosin substantively reduced symptoms.
Ciprofloxacin and tamsulosin were not effective treatments for CP/CPPS. Patients had
long-standing, refractory CP/CPPS and received trial treatments for only 6 weeks. Patients
with new diagnoses who are given longer courses of the trial treatments might respond
differently.
Phase:
Phase 2
Details
Lead Sponsor:
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)