Cinacalcet to Treat Hypercalcemia in Renal Transplant Recipients
Status:
Terminated
Trial end date:
2009-11-01
Target enrollment:
Participant gender:
Summary
Secondary hyperparathyroidism can persist following successful renal transplantation and can
cause high blood calcium, kidney dysfunction or failure and excessive bone loss among other
problems. If the condition does not resolve, surgery is frequently required to remove the
parathyroid glands, with all the inherent risks of surgery. Cinacalcet, a medicine used to
treat secondary hyperparathyroidism in patients with kidney disease, may be effective in
treating this condition in the renal transplant recipient. We will study the effect of
cinacalcet on calcium, bone and renal function in a 6 month treatment protocol.