Ciprofloxacin for the Prevention of Meningococcal Meningitis 2018

• Status: Withdrawn
• Trial end date: 2019-12-31
• Target enrollment: 0
• Participant gender: All

Summary

The trial is an interventional, cluster-randomized trial to assess the impact of oral ciprofloxacin for household and community contacts of meningitis cases on the incidence of meningitis during an epidemic.

The trial contains a nested sub-study ("resistance study") to assess the effect of a single dose of ciprofloxacin on the prevalence of fluoroquinolone-resistant enterobacteriaceae in the study area.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Epicentre
• Collaborator: Medecins Sans Frontieres, Netherlands
• Treatments: Ciprofloxacin

Criteria

Inclusion Criteria:

• Resident in a village included in the study area

Exclusion Criteria:

• Patients currently exhibiting symptoms of meningitis (to be immediately referred for further care)

• Persons with a known allergy to fluoroquinolone antibiotics.