Cisplatin Combined With Oral TS-1 in Patients With Advanced Solid Tumors With Different Degrees of Liver Dysfunction
Status:
Recruiting
Trial end date:
2025-12-20
Target enrollment:
Participant gender:
Summary
The purpose of this study is to formally characterize the pharmacokinetics (PK), safety, and
tolerability of TS-1 in combination with cisplatin in adult patients with advanced solid
tumors who have mild, moderate or severe hepatic impairment relative to patients with normal
hepatic function, as categorized by the United States National Cancer Institute organ
dysfunction working group [NCI-ODWG] criteria for hepatic dysfunction.