Overview

Cisplatin/Etoposide/Radiotherapy +/- Consolidation Docetaxel in Advanced Stage III Non-Small Cell Lung Cancer

Status:
Completed
Trial end date:
2008-03-01
Target enrollment:
Participant gender:
Summary
In a previous phase II study, patients with pathological stage IIIb (without pleural effusion) NSCLC were treated with concurrent cisplatin and etoposide plus thoracic radiotherapy followed by 3 cycles of consolidation therapy with docetaxel. Docetaxel was selected based upon a survival benefit in patients with recurrent NSCLC. This trial will evaluate the role of consolidation therapy with docetaxel in patients with unresectable stage III disease. The purpose of the trial is to evaluate survival and toxicities of the regimens employed.
Phase:
Phase 3
Details
Lead Sponsor:
Nasser Hanna, M.D.
Collaborators:
Sanofi
Walther Cancer Institute
Treatments:
Cisplatin
Docetaxel
Etoposide
Etoposide phosphate