Cisplatin HAI Study in Patients With Advanced Cancer and Dominant Liver Involvement
Status:
Completed
Trial end date:
2011-05-01
Target enrollment:
Participant gender:
Summary
The goal of this clinical research study is find the highest safe dose of cisplatin that can
be given with liposomal doxorubicin in the treatment of advanced cancer involving the liver.
PRIMARY Objectives:
To determine the toxicity and safety of a monthly cytotoxic regimen combining intraarterial
hepatic (HAI) cisplatin with systemic intravenous liposomal doxorubicin in patients with
cancer metastatic to the liver.
SECONDARY Objectives:
To document in a descriptive fashion the antitumor efficacy of monthly hepatic intraarterial
cisplatin in combination with systemic liposomal doxorubicin.