Cisplatin, Paclitaxel, and Everolimus in Treating Patients With Metastatic Breast Cancer
Status:
Completed
Trial end date:
2010-12-01
Target enrollment:
Participant gender:
Summary
RATIONALE: Drugs used in chemotherapy, such as cisplatin and paclitaxel, work in different
ways to stop the growth of tumor cells, either by killing the cells or by stopping them from
dividing. Everolimus may stop the growth of tumor cells by blocking some of the enzymes
needed for cell growth. Giving more than one drug (combination chemotherapy) together with
everolimus may kill more tumor cells.
PURPOSE: This phase I trial is studying the side effects and best dose of cisplatin,
paclitaxel, and everolimus when given together for the treatment of patients with metastatic
breast cancer.