Cisplatin, Paclitaxel, and Everolimus in Treating Patients With Metastatic Breast Cancer
Status:
Completed
Trial end date:
2017-08-01
Target enrollment:
Participant gender:
Summary
RATIONALE: Drugs used in chemotherapy, such as cisplatin and paclitaxel, work in different
ways to stop the growth of tumor cells, either by killing the cells or by stopping them from
dividing. Everolimus may stop the growth of tumor cells by blocking some of the enzymes
needed for cell growth and by blocking blood flow to the tumor. Giving cisplatin and
paclitaxel together with everolimus may kill more tumor cells.
PURPOSE: This phase I/II trial is studying the side effects of giving cisplatin and
paclitaxel together with everolimus and to see how well it works in treating patients with
metastatic breast cancer.