Cisplatin With or Without Sodium Thiosulfate in Treating Young Patients With Stage I, II, or III Childhood Liver Cancer
Status:
Completed
Trial end date:
2018-02-28
Target enrollment:
Participant gender:
Summary
RATIONALE: Drugs used in chemotherapy, such as cisplatin, work in different ways to stop the
growth of tumor cells, either by killing the cells or by stopping them from dividing.
Chemoprotective drugs, such as sodium thiosulfate, may protect normal cells from the side
effects of chemotherapy. It is not yet known whether giving sodium thiosulfate is effective
in reducing hearing damage caused by cisplatin in treating young patients with liver cancer.
PURPOSE: This randomized phase III trial is studying how well sodium thiosulfate works to
decrease hearing loss caused by cisplatin in treating young patients with stage I, stage II,
or stage III childhood liver cancer.
Phase:
Phase 3
Details
Lead Sponsor:
Children's Cancer and Leukaemia Group University of Birmingham