Citrate 4% Versus Heparinised Saline in Preventing Peripherally Inserted Central Catheter (PICC) Occlusions

• Status: Unknown status
• Trial end date: 2018-12-30
• Target enrollment: 0
• Participant gender: All

Summary

This study is a prospective, randomized, non-blinded study. 1 group will be assigned the standard arm with use of heparinised saline (10U/ml) lock in between each catheter use. This is consistent with the standard procedure of PICC care in the investigators' centre. The second group will be assigned the intervention with use of 4% citrate lock (Dirinco Citra-Lock 4%) in between each catheter use.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: National University Hospital, Singapore
• Treatments: Citric Acid

Criteria

Inclusion Criteria:

• Age more than or equal to 21 years.

• Histologic or cytologic diagnosis of haematological or oncological malignancy

• Signed informed consent from patient or legal representative

• Patients on antiplatelet therapy may be recruited to the study

Exclusion Criteria:

• Pregnancy.

• Anticoagulation - warfarin or heparin or novel oral anticoagulants

• Serious concomitant disorders that would compromise the safety of the patient or compromise the patient's ability to complete the study, at the discretion of the investigator.