Overview

Clarithromycin Plus CTd Regimen for Patients With Newly Diagnosed Multiple Myeloma

Status:
Unknown status
Trial end date:
2020-09-01
Target enrollment:
Participant gender:
Summary
Due to economic reasons, thalidomide is still widely used as a first line drug for Multiple Myeloma patients in China. However,the efficacy of CTd is still lower than the therapeutic regimens with new drugs. Clarithromycin may have partly efficacy in association with steroids and thalidomide for Multiple Myeloma patients. This multicenter, randomized, phase 3 clinical trial is proposed to explore whether clarithromycin could potentiate responsiveness of CTd (Cyclophosphamide, Thalidomide and Dexamethasone) regimen in Newly Diagnosed Multiple Myeloma patients. The trial will also evaluate the side effects caused by the combination of these drugs.
Phase:
Phase 3
Details
Lead Sponsor:
Jinling Hospital, China
Treatments:
BB 1101
Clarithromycin
Cyclophosphamide
Dexamethasone
Dexamethasone 21-phosphate
Dexamethasone acetate
Thalidomide