Clarithromycin is an Adjunct to Scaling and Root Planing

• Status: Completed
• Trial end date: 2013-12-01
• Target enrollment: 0
• Participant gender: All

Summary

The present study was done to evaluate the effect of clarithromycin as an adjunct to scaling and root planning at baseline, three months and six months intervals . Clinical, microbiological and immunological parameters were taken. Clinical parameters include gingival index , probing depth and clinical attachment level. In the present study, improved clinical and microbiological outcomes were attained using adjunctive clarithromycin, including GI, PD reduction, CAL gain and reductions in the frequency of detection of C-reactive protein, Pg, Aa. These results together with the recommended easy dosage and limited side effects make the use of this antibiotic in the treatment of periodontitis patients but only for a shorter period of time.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Panineeya Mahavidyalaya Institute of Dental Sciences & Research Centre
• Treatments: Clarithromycin

Criteria

Inclusion Criteria:

• Patients age ranged between 30- 50 years with chronic periodontitis

• Patients with Probing Depth (PD)- >5mm, Clinical Attachment Level( CAL)- >3mm

• Systemically healthy individuals

Exclusion Criteria:

• Patients below the age of 30 years

• Patients who have undergone periodontal therapy 3 months prior to study

• Active /passive smokers

• Any antibiotic use 3 months prior to study

• Pregnant women and lactating mothers

• Un co- operative/ retarded patients

• Drug allergy/ other allergies

• Any systemic diseases