Cliavist in Infectious and Degenerative Diseases of the Spine
Status:
Unknown status
Trial end date:
2009-12-01
Target enrollment:
Participant gender:
Summary
USPIO contrast enhancement results from intracellular trapping of the iron particles in
reactive cells, especially macrophages. 17FDG-PET studies have demonstrated that macrophages
are present in spine infectious diseases but are absent in spine degenerative diseases. The
aim of this work is to compare the enhancement induced by CLIAVIST in both diseases. The
absence of macrophages in degenerative lesions should help to differentiate them from
infectious lesions, who should present contrast enhancement in relation to the presence of
macrophages.