Clinical Application and Basic Study of Medicinal Fractions-based Herbal Combinations

• Status: Completed
• Trial end date: 2016-08-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to investigate the efficacy of fractions-based herbal combinations of clearing heat and promoting blood circulation treating acute ischemic stroke and the potential mechanism of it.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Yunling Zhang
• Collaborators: Huairou Hospital of Traditional Chinese Medicine; Shandong University of Traditional Chinese Medicine

Criteria

Inclusion Criteria:

• Patients with acute ischemic stroke

• Patients with fire-heat syndrome

• Stoke onset within 48 hours

• NIHSS scores range from 5 points to 25 points

• Age from forty to seventy-five,gender not limited

• Informed and signed the consent

Exclusion Criteria:

• Cardiogenic cerebral embolism,stroke caused by other reasons or the unexplained

• Patients suitable for thrombolytic therapy(rt-PA, urokinase)

• Patients have received thrombolytic therapy

• Patients with serious diseases of heart,lungs,liver,kidneys

• Patients with bleeding or bleeding tendency recently

• Pregnant or lactating women

• Pre-existing neurological or psychiatric diseases that could confound the study results

• Patients be allergic to alcohol,Ixeris of sonchifolia Hance components (KDZ injection) or Panax notoginseng saponins components (Xueshuantong injection)

• Patients have participated in other clinical trials within 3 months