Clinical Effects and Safety of 3% Diquafosol After Cataract Surgery

• Status: Completed
• Trial end date: 2015-01-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is determine whether 3% diquafosol and 0.1% sodium hyaluronate are effective and safe in the treatment of patients with dry eye after cataract surgery.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Soonchunhyang University Hospital
• Treatments: Hyaluronic Acid; Ophthalmic Solutions

Criteria

Inclusion Criteria:

• Bilateral or unilateral cataract undergoing phacoemulsification and intraocular lens (IOL) implantation at Soonchunhyang University Hospital between January 2014 and January 2015

• Patients with mild to moderate dry eye (level 1 or 2) based on the dry eye severity scale adopted by the Dry Eye Workshop (DEWS) report and who used only artificial tears occasionally

Exclusion Criteria:

• Presence of any complications after cataract surgery such as cystoid macular edema

• Patients using any topical eye drops on a regular basis

• Treatment history of dry eye beyond artificial tears

• Any ocular surgery within the prior 6 months

• Contact lens wear

• Serious ocular surface disease (e.g., Sjögren's syndrome, ocular pemphigoid, conjunctival scarring, chemical injury)

• Eyelid or lacrimal disease

• Use of concomitant medications that could cause dry eye and allergy to any of the study medications