Clinical Efficacy Of BioMin F, Colgate Sensitive Pro-Relief And Sensodyne Rapid Action Dentifrices In DH

• Status: Completed
• Trial end date: 2021-01-16
• Target enrollment: 0
• Participant gender: All

Summary

This will be multi-centered, triple blinded, randomized, four parallel treatments assigned study to compare clinical efficacy of commercially available dentifrices with placebo for immediate and sustained relief from Dentin Hypersensitivity after short term use.

Condition or disease: Dentin hypersensitivity Intervention/Treatment: Product 1; Fluoro-Calcium-Phospho-silicate based BioMin F Product 2; Pro-Argin formula based Colgate Sensitive Pro-Relief Product 3; Strontium Acetate based Sensodyne Rapid Action Product 4; Sodium Fluoride based Colgate Total

• Phase: Phase 3
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Dow University of Health Sciences
• Treatments: Calcium; Fluorides; Listerine; Sodium Fluoride

Criteria

Inclusion Criteria:

• Subjects with at least two teeth sensitive to cold, touch and air blow stimulus

• Sensitive teeth anterior to molars either due to erosions or abrasions with or without associated gingival recession

• Teeth with Linear Visual Analogue Scale (VAS) score of ≥ 4 and code 2 of Schiff Cold Air Sensitivity Scale on screening.

Exclusion Criteria:

• Subjects with worst pain response at 100mm on VAS.(Visual Analog Scale)

• Teeth with orthodontic or prosthetic appliances, Caries, restorations or cracks

• Localized or generalized gingivitis or pulpitis with heavy calculus

• Periodontal surgery in the preceding three months

• Patients using any desensitizing tooth paste or mouth wash up to six weeks before study and taking drugs like anti-inflammatory, sedatives, tranquilizers, analgesics in routine.

• Pregnant or breastfeeding females.