Clinical Efficacy and Serum Proteomic Profiling of Suan-Zao-Ren Tang for Sleep Disturbance During Methadone Maintenance

• Status: Completed
• Trial end date: 2014-03-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to evaluate the efficacy of Suan-Zao-Ren Tang in improving sleep quality, anxiety, depression, and heroin craving among methadone-maintained persons with sleep complaints.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: China Medical University, Taiwan
• Treatments: Methadone

Criteria

Inclusion Criteria:

• aged over 20 years

• patients fulfilled the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition criteria for opiate dependence

• patients had been receiving MMT for more than one month

• patients have sleep disturbance complains and with Pittsburgh sleep quality index (PSQI) of greater than six

• Must be able to signed informed consent

Exclusion Criteria:

• had received any antidepressant or neuroleptic medication

• had received any TCM treatment during the previous 30 days

• had any serious physical or mental illness

• had a significant risk of suicide

• pregnancy

• inability to read and fill out the forms for the study