Clinical Evaluation of Topical Coenzyme Q10 in Management of Oral Aphthous Ulcer

• Status: Unknown status
• Trial end date: 2018-07-01
• Target enrollment: 0
• Participant gender: All

Summary

Recurrent oral aphthous ulcer is the most common oral lesion in occurrence and one of cause is oxidative stress so investigators need to use antioxidant drugs like topical coenzyme Q10 gel to treat the lesion and more safe for the participants.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Cairo University
• Treatments: Coenzyme Q10; Ubiquinone

Criteria

Inclusion Criteria:

• Patients with free medical history and no systemic diseases16.

• Patients clinically diagnosed as suffering from symptomatic oral minor aphthous ulcers.

• Patients who agreed to take medications.

Exclusion Criteria:

• Patients suffering from any systemic disease as Crohn's disease, Behcet's disease and others.

• Anemic and leukemic patients (using complete blood count investigation)

• Patients taking systemic drugs such as systemic steroids and other immunosuppressive therapy.

• Patients treated with any oral topical medications 48h before the study27.

• Pregnant and lactating mothers.