Clinical Evaluation on the Therapeutic Effect of Acupuncture Treatment for Alzheimer's Disease
Status:
Recruiting
Trial end date:
2022-06-30
Target enrollment:
Participant gender:
Summary
The objective of this proposed study is to evaluate the effect and safety of acupuncture
combined therapy on cognitive function, daily living ability and quality of life of
Alzheimer's disease by using the international dementia certification scale. In this 12-week,
assessor-blind, a Multi-center randomized, controlled study of acupuncture as additional
treatment with Donepezil, a total of 180 patients with Alzheimer's disease will be recruited.
The patients will be randomly assigned to acupuncture combined with Donepezil (n =90) or
Donepezil treatment (n =90). (36 sessions, 3 sessions a week). Changes in the cognition over
time measured using ADAS-cog is the primary outcome. MMSE, ADCS-ADL and QOL-AD are the
secondary outcomes. The study will be conducted at LongHua Hospital Shanghai University of
Traditional Chinese Medicine, Huashan Hospital Fudan University, and Mental Health Center
Shanghai Jiao Tong University School of Medicine.
Phase:
N/A
Details
Lead Sponsor:
Shanghai University of Traditional Chinese Medicine