Overview

Clinical Pharmacology Study of Brentuximab Vedotin (SGN-35)

Status:
Completed
Trial end date:
2012-05-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to identify brentuximab vedotin drug-drug interactions in patients with CD30-positive cancers and to determine the main route of excretion. The study will also assess blood drug levels in patients with renal or hepatic impairment (special populations).
Phase:
Phase 1
Details
Lead Sponsor:
Seagen Inc.
Seattle Genetics, Inc.
Collaborator:
Millennium Pharmaceuticals, Inc.
Treatments:
Antibodies
Antibodies, Monoclonal
Brentuximab Vedotin
Ketoconazole
Midazolam
Rifampin