Overview

Clinical Pharmacology Study of Oral Edaravone in Healthy Adult Males (Drug Interaction Study and Preliminary Regimen-Finding Study)

Status:
Completed

Trial end date:
2019-01-08

Target enrollment:

Participant gender:

Summary

- Cohort 1: To evaluate the drug interactions, safety, and tolerability of oral edaravone when coadministered with rosuvastatin, sildenafil or furosemide in healthy adult males - Cohort 2: To evaluate the pharmacokinetics, safety, and tolerability of oral edaravone in healthy Japanese and Caucasian adult males

Phase:

Phase 1

Details

Lead Sponsor:

Mitsubishi Tanabe Pharma Corporation

Treatments:

Edaravone
Furosemide
Rosuvastatin Calcium
Sildenafil Citrate