Clinical Research of the Prognostic Influence of NSAIDS's Anti-inflammatory Effect on Senior Patients With Hip Fracture

• Status: Unknown status
• Trial end date: 2015-12-01
• Target enrollment: 0
• Participant gender: All

Summary

With the development of society, aged population is growing. Hip fracture is the most common disease for aged people. With the life being longer than before, incidence of this disease is growing. The mortality of this disease is high-- almost 10% patients will die within 1 month, about 1/3 of patients will die within 12 months. About 20%-30% aged people who have hip fracture will die within one year.

The damaged organs caused by excessive inflammatory is one of possible reasons to cause higher mortality. Therefore, the investigators imagined that if they gave medicines to patients in time to reduce the inflammatory level, the inflammatory might have less effects on organs, and the recovery could be improved.

The investigators hypothesis on the basic research: the anti-inflammatory function of non steroidal antiinflammatory drugs (NSAIDs) can inhibit the inflammatory level of elderly hip fracture, so as to improve the recovery level and reduce the complicating disease and mortality. The investigators designed a clinic study to research NSAIDS' effects on inflammatory level and prognosis of elderly hip fracture.

• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Beijing Army General Hospital
• Treatments: Acetaminophen; Acetaminophen, hydrocodone drug combination; Anti-Inflammatory Agents; Celecoxib; Oxycodone

Criteria

Inclusion Criteria:

• age > 60 years old,

• new patients with hip fracture(intertrochanteric fractures and femoral neck fractures),

• sign informed consent,

• can be followed up

Exclusion Criteria:

• have autoimmune disease,

• with blood disease, a history of thrombosis,

• with sulfonamides, aspirin or celebrex race Levin allergies,

• pathological fracture