Clinical Study of Curcumin in Preventing Postoperative Adhesion of Bilateral Vocal Cords

• Status: Recruiting
• Trial end date: 2026-12-31
• Target enrollment: 0
• Participant gender: All

Summary

To provide a novel therapy idea and method to solve the clinical problem of postoperative adhesion of bilateral vocal cords, patients enrolled in this study will be applied with curcumin on both wound sites of bilateral vocal cords after the surgery on the bilateral vocal cord endoscopically.

• Phase: Phase 1/Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Eye & ENT Hospital of Fudan University
• Treatments: Curcumin; Mitomycin; Mitomycins

Criteria

Inclusion Criteria:

1. Patients with bilateral vocal cord diseases who are going to undergo resection of bilateral vocal cord lesions endoscopically.

2. Patients with bilateral vocal cord adhesion who are going to undergo incision of bilateral vocal cord adhesion endoscopically.

Exclusion Criteria:

1. Patients with other laryngeal diseases.

2. Patients with cardiac and pulmonary insufficiency.

3. Patients unable to cooperate with the follow-up on time after surgery.

4. Patients who refuse to sign the informed consent after notification.

5. Patients who have a severe allergic disease or allergic history to a variety of drugs.

6. Other circumstances that are not appropriate to be included in the clinical trial.