Clinical Study of Depodur Efficacy in Decreasing Post Operative Pain After Off Pump Coronary Artery Bypass Grafting (OP-CABG)

• Status: Withdrawn
• Trial end date: 2008-04-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to determine whether epidural Depodur alleviates the pain of OP-CABG surgery. This includes pain associated with sternotomy, retraction, dissection and other tissue insults, as well as the induced inflammatory system and effects from prolonged ventilation in the ICU setting.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Drexel University College of Medicine

Criteria

Inclusion Criteria:

• Male or Female, 18-99 years old

• All patients who will have surgery for OP-CABG

Exclusion Criteria:

• Pregnant females

• Patients with allergy to morphine

• Patients nursing an infant

• Patients with migraine headaches

• Patients taking Coumadin within 7 days or demonstrating INR > 13

• Patients taking Heparin unless documented normal partial thromboplastin time

• Patients taking Clopidogrel in previous 7 days

• Patients taking Ticlopidine in previous 14 days

• Patients taking Aspirin in previous 48 hours

• Patients receiving low molecular weight heparin therapy within 24 hours previous

• Patients with Narcolepsy and/or sleep apnea

• Patients on chronic opioid therapy

• Patients participating in another study