Clinical Study of Human Umbilical Cord Mesenchymal Stem Cells in the Treatment of Premature Ovarian Insufficiency

• Status: Recruiting
• Trial end date: 2023-12-01
• Target enrollment: 0
• Participant gender: Female

Summary

This study was a single-center, randomized, controlled prospective study. Those who had premature ovarian failure and who had fertility requirements were enrolled in the study. To determine the efficacy and safety of umbilical cord mesenchymal stem cells in the treatment of patients with POI.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Li-jun Ding
• Treatments: Hormones

Criteria

Inclusion Criteria:

1. Those who meet the POF diagnostic criteria and have no spontaneous follicular activity;

2. Married, 20 years old ≤ age < 40 years old;

3. The average diameter of each ovary is > 10 mm;

4. Have agreed to sign the informed consent form.

Exclusion Criteria:

1. Female and/or male chromosomal abnormalities;

2. Endometriosis, adenomyosis;

3. Postoperative ovarian borderline or malignant tumor;

4. Uterine dysplasia;

5. Associated with female autoimmune disease or other serious internal surgical diseases;

6. hormone replacement contraindications;

7. In the past 1 year, had received an experimental study of premature ovarian failure in the external hospital;

8. Male azoospermia or severe oligozoospermia.