Overview

Clinical Study of Umbilical Cord Blood Mononuclear Cells (UCB-MNCs) in the Treatment of Traumatic Fracture Healing

Status:
Recruiting
Trial end date:
2022-12-10
Target enrollment:
0
Participant gender:
All
Summary
The aim of this study is to explore the effectiveness and safety of umbilical cord blood mononuclear cells in promoting traumatic fracture healing.
Phase:
N/A
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Qianfoshan Hospital
Collaborator:
Shandong Qilu Stem Cells Engineering Co., Ltd.
Criteria
Inclusion Criteria:

- Traumatic long bone fracture.

- Noninfectious bone nonunion, delayed bone union.

- 3 months after the operation of the fracture, the examination showed no callus growth,
no signs of progressive repair at the fracture site, fracture piece space < 5mm.

- No shortening, angulation and displacement.

- There was no obvious callus growth 8 months after local bone grafting.

Exclusion Criteria:

- There are infection foci at and near the fracture end after fracture.

- 3 months after the fracture, tests showed partial callus growth.

- Combining shortening, angulation and displacement phenomena.

- Partial callus grew 8 months after local bone grafting.