Clinical Study on the Prevention of Driver Gene Negative II-IIIa Lung Cancer Recurrence and Metastasis by Staged Chinese Herbal Medicine Combined With Chemotherapy and Immune Checkpoint Inhibitors

• Status: Not yet recruiting
• Trial end date: 2026-06-30

Summary

This project adopts a prospective, multicenter, randomized controlled clinical study to investigate the treatment of TCM in postoperative patients with driver gene negative lung cancer, according to two phases of postoperative adjuvant therapy: (i) chemotherapy phase immunotherapy phase. In this study, 367 patients (183 in the control group and 184 in the trial group) will be observed over 4 years, and the quality of life, toxic effects and safety of this therapy will be investigated. This study will provide evidence-based evidence for the establishment and optimization of a new model of postoperative staged TCM with adjuvant chemo-immunotherapy for lung cancer.

• Phase: N/A

Details

• Lead Sponsor: Shanghai University of Traditional Chinese Medicine
• Collaborators: Fudan University; Ruijin Hospital; Shanghai Chest Hospital; Shanghai Pulmonary Hospital, Shanghai, China; Shanghai Zhongshan Hospital