Clinical Trial Comparing Endometrial Transformation With Subcutaneous Progesterone Versus Intramuscular Progesterone

• Status: Completed
• Trial end date: 2016-01-01
• Target enrollment: 0
• Participant gender: Female

Summary

Study the endometrial predecidualization by using subcutaneous progesterone 25 mg/day versus intramuscular progesterone 50 mg/day, to determine whether there are differences in the endometrial transformation and endometrial receptivity.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: IVI Barcelona
• Treatments: Progesterone

Criteria

Inclusion Criteria:

• Female aged between 18 and 34 years

• BMI between 18 and 28 kg/m2

• Endometrial thickness > 7 mm the day of progesterone treatment initiation (day of follicular puncture)

• Follicular maturation with a single bolus of GnRH agonist

• Egg donors who undergo a cycle of ovarian stimulation in the IVI Barcelona Centre

• Egg donors selected in accordance with the requirements of Law 14/2006 of 26 May 2006 on Assisted Human Reproduction Techniques

• Informed consent has been signed and dated

Exclusion Criteria:

• Known allergy to progesterone formulations or their excipients

• Known allergy to estrogens

• Known thrombophilias

• Alcohol, drug or psychotropic medication dependence

• Concurrent participation in another study

• Concomitant medication that may interfere with the study medication and ovarian stimulation

• Failure to comply with the requirements for egg donors in accordance with Law 14/2006 of 26 May 2006 on Assisted Human Reproduction Techniques