Clinical Trial Studying the Effects of Spironolactone on Heart and Skeletal Muscle Function in Chronic Alcoholics

• Status: Suspended
• Trial end date: 2011-12-01
• Target enrollment: 0
• Participant gender: Male

Summary

Chronic alcoholics suffer from weak skeletal and cardiac muscle. The investigators have discovered a beneficial effect of spironolactone-treatment in that regard. Therefore, a double blind placebo controlled study is conducted, to examine the effects of spironolactone on cardiac and skeletal muscle-function in chronic alcoholics.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Aarhus
• Treatments: Spironolactone

Criteria

Inclusion Criteria:

• Alcoholism, male gender

Exclusion Criteria:

• Spironolactone treatment

• Tense ascites

• Hepatic encephalopathy

• Dementia

• Cancer

• Severe psychiatric disease

• Untreated thyroid disease

• Maltreated diabetes

• Spironolactone contraindications

• Kidney failure