Clinical Trial of 0.0003% Calcitriol, 0.1% Tacrolimus, and Petrolatum for the Treatment of Pityriasis Alba
Status:
Completed
Trial end date:
2011-01-01
Target enrollment:
Participant gender:
Summary
Pityriasis alba (PA) is a frequent cause of consultation in tropical areas due to its chronic
course, trend to relapse and aesthetic impact. Currently, no treatment is widely accepted.
The objective is to assess the calcitriol and tacrolimus ointment efficacy in the treatment
of PA compared with petrolatum. Twenty lesions on the face greater than 3 cm, in individuals
of phototype IV-V, aged 3-18 years are going to be randomly assigned to receive petrolatum,
calcitriol, and tacrolimus twice daily. No photoprotection is going to be indicated, and
hygienic habits will not be modified. Patients will be evaluated at baseline and for 9 weeks,
by means of Transepidermal Water Loss (TEWL), colorimetry, clinically and by photography
control.