Clinical Trial of Cinobufacini Injection Combined With Oxaliplatin Regimen on Gastrointestine Carcinoma
Status:
Unknown status
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
The clinical trail of Cinobufacini injection combined with Oxaliplatin regimen on
gastrointestine carcinoma.This trail is randomized controled.Patients are diagnosed
gastrointestinal cancer based on pathology or cell biology.They are randomized into 2
groups:both groups receive Oxaliplatin regimen.The treatment group receives Cinobufotalin
20ml mixed with 5% Glucose injection 500ml from the first day of chemotherapy until seven
days in addition to the chemotherapy.The control group only receive the same chemotherapy
with the treatment group.Both group have the same adjuvant therapy.Mainly to study of
oxaliplatin into Cinobufacini injection leads to the influence of the peripheral nerve
toxicity.Clinical evaluation includes neural electrophysiological test,chemotherapy drug
toxicities,quality of life(QOL),etc.Blood biochemistry tests mainly include inflammatory
cytokines,peroxidase reaction,immune cell number ratio and stress hormone,etc.