Overview Clinical Trial to Investigate the Effect of Proton Pump Inhibitor on the Pharmacokinetics and Pharmacodynamics of Metformin Status: Completed Trial end date: 2012-12-01 Target enrollment: Participant gender: Summary This study aims to investigate the effect of proton pump inhibitor on the pharmacokinetics and pharmacodynamics of metformin in healthy Korean men. Phase: Phase 1 Details Lead Sponsor: Seoul National University HospitalTreatments: MetforminPantoprazoleProton Pump InhibitorsRabeprazole