Clinical Trials With a Local Anesthetic Lozenge for the Treatment of Chronic Oral Pain

• Status: Terminated
• Trial end date: 2014-08-01
• Target enrollment: 0
• Participant gender: All

Summary

The aim of the project is to do a fase two trial, where the effect of a local anesthetic lozenge will be tested in regard to oral pain, dryness of the mouth, irregularity of taste as well as investigate a potential antiinflammatory effect in patients with burning mouth syndrome, Sjögrens syndrome and lichen planus.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Hvidovre University Hospital
• Collaborator: Oracain II Aps
• Treatments: Anesthetics; Anesthetics, Local; Bupivacaine

Criteria

Inclusion Criteria:

• Diagnosed with burning mouth syndrome, Sjögrens syndrome or lichen planus

• All fertile women need to use save contraception

• Age between 18 and 75 years

• Able to speak, read and understand the danish language

• Must be informed orally and release a written consent and a signed authorization statement

Exclusion Criteria:

• Pregnant or breastfeeding women

• Known allergy to bupivacaine or other local anesthetics of the amide type

• Active infection which requires antibiotic treatment

• Patients in immune suppressive treatment