Clinical & Biochemical Effect of Atorvastatin in Nano Particles Gel in Periodontitis Treatment

• Status: Completed
• Trial end date: 2022-06-30
• Target enrollment: 0
• Participant gender: All

Summary

Periodontitis is a destructive chronic inflammatory disease characterized by periodontium damage and pocket formation between the tooth and the gingival margin resulting in ultimate tooth loss. Various topical anti-inflammatory drugs were used to treat inflammation in periodontitis. Introducing atorvastatin as a novel remedy for periodontitis treatment necessitates developing a syringeable modified delivery system capable of targeting inflammation within the periodontal pockets.

• Phase: Phase 1
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Misr University for Science and Technology
• Treatments: Atorvastatin; Calcium

Criteria

Inclusion Criteria:

• Systemically healthy patients

• Patients with moderate periodontitis

Exclusion Criteria:

• Pregnant women

• Lactating women

• Patients with chronic diseases